Proteus vulgaris phage NTCC? vB\_PvuS\_Pm34, RP6/RP7,PV22普通变形杆菌噬菌体-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
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NTCC? Proteus vulgaris phages are bacteriophages, or viruses that infect and replicate within Proteus vulgaris bacteria. These phages, like vB\_PvuS\_Pm34, have been studied for their lytic activity and potential use in phage therapy. They are known for their ability to lyse or kill Proteus bacteria, and some phages, like RP6 and RP7, have shown effectiveness against both Proteus vulgaris and Proteus mirabilis. Furthermore, some phages, such as phage PV22, have been found to bind to and inhibit the growth of Campylobacter jejuni, a bacteria that can colonize chicken intestines.
Here's a more detailed breakdown:
Key Characteristics of Proteus vulgaris Phages:
- Lytic Activity:Phages like vB\_PvuS\_Pm34 and RP6/RP7 are lytic, meaning they infect and kill their host bacteria.
- Host Range:Some phages have a broad host range, like RP6/RP7, which can infect both Proteus vulgaris and Proteus mirabilis.
- Stability:Phages are generally stable and can withstand various pH and temperature conditions.
- Genome:The genomes of Proteus phages have been sequenced, revealing information about their genes and potential for phage therapy.
- Potential Applications:Proteus phages are being investigated for their potential use in phage therapy, a treatment for bacterial infections, particularly those caused by antibiotic-resistant strains.
Examples of Proteus vulgaris Phages:
- vB\_PvuS\_Pm34:A novel lytic phage isolated from sanitary sewage, with a 39,558 bp genome and an icosahedral capsid.
- RP6 and RP7:Lytic phages isolated from university hospital sewage, effective against both Proteus vulgaris and Proteus mirabilis.
- Phage PV22:A phage that binds to and inhibits the growth of Campylobacter jejuni, potentially useful for reducing bacterial colonization in chickens.
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